论文标题
基于可调的声学镜头和光纤延迟网络的平行多焦点光学显微镜
Parallel multifocus optical-resolution photoacoustic microscopy based on tunable acoustic gradient lens and fiber delay network
论文作者
论文摘要
我们使用可调的声学梯度(TAG)镜头和脉冲延迟方法开发了具有扩展景深(DOF)的多焦点光学显微镜(MPAM)。 TAG透镜旨在控制激光束的差异角。三个具有不同长度的纤维用于输出三个激光脉冲,延迟时间不同。通过控制激光脉冲的火时间,我们可以通过系统中的一个A线数据采集在系统中的标签镜头中获得三个焦点。使用垂直倾斜碳纤维测量的MPAM的DOF约为775微米。横向分辨率估计为2.8微米。幻影由钨电线和斑马鱼组成,用于验证我们系统的较大场地。
We developed a multifocus optical-resolution photoacoustic microscope (MPAM) with extended depth of field (DoF) by using a tunable acoustic gradient (TAG) lens and a pulse delay method. TAG lens is designed to control the divergence angle of the laser beam. Three fibers with different length are used to output three laser pulses with different delay time. By controlling the fire time of the laser pulses, we can get three focal spot through TAG lens in our system in one A-line data acquisition. The DoF of MPAM measured using a vertically tilted carbon fiber is about 775 micrometers. The lateral resolution is estimated to be 2.8 micrometers. A phantom consists of tungsten wires and a zebrafish is used to verify the large depth-of-field of our system.