论文标题
在滑行测定中的半灵性聚合物：再入过渡，营业额和活动的作用
Semiflexible polymer in a gliding assay: reentrant transition, role of turnover and activity
论文作者
论文摘要
我们考虑了一个可扩展的半融合细丝在两个维度上移动的模型，该模型是在运动蛋白的运动性测定方面明确表示为活动谐波接头的模型。它们的头随着捕获半径内的聚合物段的随机结合，并在脱离之前以定向方式沿灯丝延伸。扩展率和脱离率都取决于负载，并在细丝上产生一个主动驱动器。细丝经历了从开放链到螺旋构象的一阶相变，并在主动延伸和周转率中都表现出重点行为，定义为附着速率的比率。与相变相关，聚合物的大小和形状在非单调方面变化，相关的自相关函数显示双指数衰减。相应的相关时间显示了螺旋的主导地位的最大值。定向动力学捕获了螺旋的旋转，其相关时间与作为权力定律的活动衰减。
We consider a model of an extensible semiflexible filament moving in two dimensions on a motility assay of motor proteins represented explicitly as active harmonic linkers. Their heads bind stochastically to polymer segments within a capture radius, and extend along the filament in a directed fashion before detaching. Both the extension and detachment rates are load-dependent and generate an active drive on the filament. The filament undergoes a first order phase transition from open chain to spiral conformations and shows a reentrant behavior in both the active extension and the turnover, defined as the ratio of attachment-detachment rates. Associated with the phase transition, the size and shape of the polymer changes non-monotonically, and the relevant autocorrelation functions display double-exponential decay. The corresponding correlation times show a maximum signifying the dominance of spirals. The orientational dynamics captures the rotation of spirals, and its correlation time decays with activity as a power law.
