论文标题
到目前为止，我们对DNA力学有什么了解？
What do we know about DNA mechanics so far?
论文作者
论文摘要
除携带遗传信息外，DNA分子在多种生物过程中起着至关重要的作用，并在药物设计，纳米技术和纳米电子学中找到了应用。由于生理和非生理环境，该分子在力的影响下经历了重要的结构过渡。在这里，我们总结了有关在各种环境条件下，从武力下的结构过渡和机制及其弹性特性的模拟和单分子实验中获得的见解，并讨论了吸引人的未来方向。
The DNA molecule, apart from carrying the genetic information, plays a crucial role in a variety of biological processes and find applications in drug design, nanotechnology and nanoelectronics. The molecule undergoes significant structural transitions under the influence of forces due to physiological and non-physiological environments. Here, we summarize the insights gained from simulations and single-molecule experiments on the structural transitions and mechanics of DNA under force, as well as its elastic properties, in various environmental conditions, and discuss appealing future directions.
