论文标题

基于术前脑电图信号的单个丙泊酚需求的预测

Prediction of Individual Propofol Requirements based on Preoperative EEG Signals

论文作者

Kweon, Young-Seok, Lee, Minji, Won, Dong-Ok, Seo, Kwang-Suk

论文摘要

由于产能过剩和容量较低,因此必须给患者提供足够数量的丙泊酚进行安全手术。但是,丙泊酚的敏感性因患者而异,因此很难确定麻醉的丙泊酚需求。本文旨在基于术前脑电图(EEG)提出丙泊酚需求的神经生理预测指标。我们利用了典型的相关性分析,该分析涉及有关丙泊酚需求的信息量。结果表明,术前的EEG包括可以解释丙泊酚需求的因素。具体而言,额叶和后部区域具有有关丙泊松要求的重要信息。此外,与中部地区的α功率不同,基线和无意识期之间的额叶和后部区域的功率显着不同。这些发现表明了术前脑电图可以预测丙泊酚的需求的潜力。

The patient must be given an adequate amount of propofol for safe surgery since overcapacity and low capacity cause accidents. However, the sensitivity of propofol varies from patient to patient, making it very difficult to determine the propofol requirements for anesthesia. This paper aims to propose a neurophysiological predictor of propofol requirements based on the preoperative electroencephalogram (EEG). We exploited the canonical correlation analysis that infers the amount of information on the propofol requirements. The results showed that the preoperative EEG included the factor that could explain the propofol requirements. Specifically, the frontal and posterior regions had crucial information on the propofol requirements. Moreover, there was a significantly different power in the frontal and posterior regions between baseline and unconsciousness periods, unlike the alpha power in the central region. These findings showed the potential that preoperative EEG could predict the propofol requirements.

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